Flowers for Algernon by Daniel Keyes 5 *
I cannot recommend this book highly enough.
A successful experimental brain operation on lab mouse, Algernon, leads to a human trial on Charlie, in order to increase his very low IQ. Charlie relates his experience in a poor level of literacy at the beginning and end of the story, whilst rising to a fantastically high level in the middle of it. It is an astonishing concept, possibly analogous of its time in late 1950s New York, beautifully executed. This book can be studied, appreciated and loved from many angles. It is moving, fascinating and incredibly clever.